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Augmentation of myocardial blood flow in hypertensive heart disease by angiotensin antagonists

A comparison of lisinopril and losartan

Olakunle O. Akinboboye, MD, MPH, FACC^*,*, R. u-Ling Chou, PhD and Steven R. Bergmann, MD, PhD, FACC

^* Saint Francis Hospital, Roslyn, State University of New York at StonyBrook, Roslyn, New York, USA
Division of Cardiology, Columbia University, New York, New York, USA.

View larger version (26K): [in a new window]   Figure 1 (a) Pre- and post-treatment resting flow values in patients treated with angiotensin-converting enzyme inhibitors (ACEIs). (b) Pre- and post-treatment maximal flow values in patients treated with ACEIs. (c) Pre- and post-treatment myocardial perfusion reserve in patients treated with ACEIs.

View larger version (28K): [in a new window]   Figure 2 (a) Pre- and post-treatment resting flow values in patients treated with angiotensin-receptor blockers (ARBs). (b) Pre- and post-treatment maximal flow values in patients treated with ARBs. (c) Pre- and post-treatment myocardial perfusion reserve in patients treated with ARBs.

View larger version (32K): [in a new window]   Figure 3 Pre- and post treatment hyperemic flow values in patients treated with angiotensin-receptor blockers (ARBs) (left two bars) and in those treated with angiotensin-converting enzyme (ACE) inhibitors (right two bars) compared with controls (middle).