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The prognostic value of serum myoglobin in patients with non–ST-segment elevation acute coronary syndromes

Results from the TIMI 11B and TACTICS-TIMI 18 studies

James A. de Lemos, MD^*,*, David A. Morrow, MD, MPH^*, C. Michael Gibson, MD, MS, FACC^*, Sabina A. Murphy, MPH^*, Marc S. Sabatine, MD^*, Nader Rifai, PhD^||, Carolyn H. McCabe, BS^*, Elliott M. Antman, MD, FACC^*, Christopher P. Cannon, MD, FACC^* and Eugene Braunwald, MD, FACC^*

^* Thrombolysis In Myocardial Infarction (TIMI) Study Group, Boston, Massachusetts, USA
Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical School, Dallas, Texas, USA
Cardiovascular Division, Brigham and Women’s Hospital, Boston, Massachusetts, USA
Harvard Clinical Research Institute, Boston, Massachusetts, USA
^|| Children’s Hospital, Boston, Massachusetts, USA

View larger version (15K): [in a new window]   Figure 1 Comparison of myoglobin and troponin I for predicting death and nonfatal myocardial infarction (MI) in the combined TIMI 11B/TACTICS-TIMI 18 dataset. Open bar = normal myoglobin (110 µg/l); solid bar = elevated myoglobin (>110 µg/l). cTnI = cardiac troponin I. For acronym definition, see Abbreviation box.