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J Am Coll Cardiol, 2002; 40:2117-2121
© 2002 by the American College of Cardiology Foundation
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Early statin therapy restores endothelial function in children with familial hypercholesterolemia

Saskia de Jongh, MD*{dagger},§,*, Marc R. Lilien, MD{ddagger},§, Jos op’t Roodt, MSc{ddagger}, Erik S. G. Stroes, MD, PhD{dagger}, Henk D. Bakker, MD, PhD*{dagger} and John J. P. Kastelein, MD, PhD{dagger}

* Emma Children’s Hospital, AMC, Amsterdam, Netherlands
{dagger} Department of Vascular Medicine, Academic Medical Center Amsterdam, Netherlands
{ddagger} Wilhelmina Children’s Hospital, Utrecht, Netherlands



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  		Figure 1 Flow-mediated dilation (FMD) (%) placebo versus simvastatin (familial hypercholesterolemia [FH]) at baseline and 28 weeks. Striped bar = baseline; white bar = 28 weeks. *p < 0.0001 vs. baseline; {dagger}p < 0.05, {Delta} FMD placebo vs. {Delta} FMD simvastatin.

 




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