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Is the mitral valve area flow-dependent in mitral stenosis?

A dobutamine stress echocardiographic study

Jagdish C. Mohan, MD^*, Ayan R. Patel, MD, FACC, Rajiv Passey, MD^*, Dinesh Gupta, MD^*, Manoj Kumar, MD^*, Ramesh Arora, MD^* and Natesa G. Pandian, MD, FACC^,*

^* Department of Cardiology, G. B. Pant Hospital, New Delhi, India
Cardiovascular Imaging and Hemodynamic Laboratory, Tufts-New England Medical Center, Boston, Massachusetts, USA

View larger version (30K): [in a new window]   Figure 1 Changes in cardiac output during dobutamine administration in group I (A) and group II (B). *p < 0.0001 compared to baseline.

View larger version (30K): [in a new window]   Figure 2 (A) Changes in planimetered mitral valve area (MVA) during dobutamine infusion in group I. (B) Changes in MVA derived by the pressure half-time method during dobutamine infusion in group I. *p < 0.0001, p = 0.0002 compared with baseline.

View larger version (29K): [in a new window]   Figure 3 (A) Changes in planimetered mitral valve area (MVA) during dobutamine infusion in group II. (B) Changes in MVA derived by the pressure half-time method during dobutamine infusion in group II. *p = 0.0035, p = 0.001 compared with baseline.