HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Blake, G. J. Articles by Kuntz, K. M. Search for Related Content PubMed PubMed Citation Articles by Blake, G. J. Articles by Kuntz, K. M.

Projected life-expectancy gains with statin therapy for individuals with elevated c-reactive protein levels

Gavin J. Blake, MB, MSc, MRCP^*, Paul M. Ridker, MD, MPH^*,* and Karen M. Kuntz, ScD^,*

^* Center for Cardiovascular Disease Prevention, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA;
Center for Risk Analysis, Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts, USA

View larger version (13K): [in a new window]   Figure 1 Gains in life expectancy among men (A) and women (B) in the low-density lipoprotein (LDL)/high C-reactive protein (CRP) group, according to the rate of myocardial infarction (MI) and efficacy of statin therapy for the prevention of MI in the low LDL/high CRP group. Line with triangles = 60% efficacy; line with circles = 45% efficacy; line with squares = 30% efficacy. AFCAPS/TexCAPS = Air Force/Texas Coronary Atherosclerosis Prevention Study; WOSCOPS = West of Scotland Coronary Prevention Study.

View larger version (11K): [in a new window]   Figure 2 Results of sensitivity analysis. Each bar indicates the effect on estimated gains in life expectancy associated with statin therapy in 58-year-old men and women in the low-density lipoprotein (LDL)/high C-reactive protein (CRP) group, when a range of different values (shown in parentheses) is used for the indicated variables. The results for men are shown by solid bars and the results for women by open bars. MI = myocardial infarction.