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The presence of African American race predicts improvement in coronary endothelial function after supplementary L-arginine

Jan L. Houghton, MD, FACC^*,*, Edward F. Philbin, MD, FACC^*, David S. Strogatz, PhD, Mikhail T. Torosoff, MD^*, Steven A. Fein, MD, FACC^*, Patricia A. Kuhner, RN^*, Vivienne E. Smith, MD, FACC^* and Albert A. Carr, MD

^* Division of Cardiology, Department of Medicine, Albany Medical College, Albany, New York, USA
School of Public Health, State University of New York at Albany, Albany, New York, USA
Augusta Preventive Cardiology, Inc., Augusta, Georgia, USA

View larger version (37K): [in a new window]   Figure 1 Individual peak percent increase in coronary blood flow above baseline in response to acetylcholine alone (AChHb) and then after repeated administration of acetylcholine following infusion of L-arginine (AChH after L-Arg) is shown in 33 African Americans (left panel) and in 33 matched white subjects (right panel). p = 0.004.

View larger version (22K): [in a new window]   Figure 2 Absolute percentile change in coronary blood flow in response to peak acetylcholine infusion after L-arginine infusion compared with peak acetylcholine infusion alone. Data are shown for 13 African American and 13 matched white women; for 20 African American and 20 matched white men; and for the total population of 33 African American and 33 matched white subjects.