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J Am Coll Cardiol, 2002; 39:1020-1025
© 2002 by the American College of Cardiology Foundation
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Intensive cholesterol reduction lowers blood pressure and large artery stiffness in isolated systolic hypertension

Kathryn E. Ferrier, BSc(Hons)*, Michael H. Muhlmann, MBBS, FRACP*, Jean-Philippe Baguet, MD, PhD*, James D. Cameron, MD, MEngSc*, Garry L. Jennings, MD, FRACP*, Anthony M. Dart, BChBM, DPhil, FRCP* and Bronwyn A. Kingwell, PhD*,*

* Alfred and Baker Medical Unit, Baker Medical Research Institute, Melbourne, Victoria, Australia



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Figure 1 Systemic arterial compliance (SAC) after placebo administration (open bar) and after atorvastatin treatment (solid bar). *ptreatment = 0.03, porder = 0.48, pinteraction = 0.98). Data are presented as the mean value ± SEM.

 


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Figure 2 Rest blood pressure of the brachial artery after placebo administration and after atorvastatin treatment. The top portion of each bar represents systolic blood pressure (SBP); the white band in the middle represents mean arterial pressure (MAP); and the base portion of each bar represents diastolic blood pressure (DBP). Each pressure variable was analyzed in a separate two-way repeated measures analysis of variance and was significantly lower after atorvastatin treatment (*ptreatment <0.05 for SBP, DBP and MAP; both porder and pinteraction were >0.05 for all variables; see text for individual p values). Data are presented as the mean value ± SEM.

 




 
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