Intensive cholesterol reduction lowers blood pressure and large artery stiffness in isolated systolic hypertension
Kathryn E. Ferrier, BSc(Hons)*,
Michael H. Muhlmann, MBBS, FRACP*,
Jean-Philippe Baguet, MD, PhD*,
James D. Cameron, MD, MEngSc*,
Garry L. Jennings, MD, FRACP*,
Anthony M. Dart, BChBM, DPhil, FRCP* and
Bronwyn A. Kingwell, PhD*,*
* Alfred and Baker Medical Unit, Baker Medical Research Institute, Melbourne, Victoria, Australia

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Figure 1 Systemic arterial compliance (SAC) after placebo administration (open bar) and after atorvastatin treatment (solid bar). *ptreatment = 0.03, porder = 0.48, pinteraction = 0.98). Data are presented as the mean value ± SEM.
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Figure 2 Rest blood pressure of the brachial artery after placebo administration and after atorvastatin treatment. The top portion of each bar represents systolic blood pressure (SBP); the white band in the middle represents mean arterial pressure (MAP); and the base portion of each bar represents diastolic blood pressure (DBP). Each pressure variable was analyzed in a separate two-way repeated measures analysis of variance and was significantly lower after atorvastatin treatment (*ptreatment <0.05 for SBP, DBP and MAP; both porder and pinteraction were >0.05 for all variables; see text for individual p values). Data are presented as the mean value ± SEM.
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