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Pharmacologic preconditioning of estrogen by activation of the myocardial adenosine triphosphate-sensitive potassium channel in patients undergoing coronary angioplasty

Tsung-Ming Lee, MD, FESC^*,*, Sheng-Fang Su, PhD, Tsai-Fwu Chou, MD and Chang-Her Tsai, MD, PhD

^* Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
Surgery, Cardiology Section, National Taiwan University Hospital, Taipei, Taiwan
Department of Clinical Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Department of Surgery, Municipal Jen-Ai Hospital, Taipei, Taiwan

View larger version (14K): [in a new window]   Figure 1 Summary of study protocol. Black boxes = period of balloon inflation; arrows = intracoronary electrocardiograms and chest anginal score; arrowheads = lactate measurements from the great cardiac vein and the aorta simultaneously. Est = estrogen; Glib = glibenclamide; PC = preconditioning; S = seconds.