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Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure

Marc A. Silver, MD^*,*, Darlene P. Horton, MD, Jalal K. Ghali, MD and Uri Elkayam, MD

^* Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, Illinois, USA
Scios Inc., Sunnyvale, California, USA
Cardiac Centers of Louisiana, Shreveport, Louisiana, USA
Los Angeles County-University of Southern California Medical Center, Los Angeles, California, USA

View larger version (14K): [in a new window]   Figure 1 Study schema. IV = intravenous.

View larger version (15K): [in a new window]   Figure 2 Kaplan-Meier estimate of mortality. Circles = dobutamine (n = 58); squares = nesiritide 0.6 µg/kg 0.030 µg/kg per min (n = 100); triangles = nesiritide 0.3 µg/kg 0.015 µg/kg per min (n = 103).