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Strain rate measurement by doppler echocardiography allows improvedassessment of myocardial viability inpatients with depressed left ventricular function

Rainer Hoffmann, MD^*,*, Ertunc Altiok^*, Bernd Nowak, MD, Nicole Heussen, Harald Kühl, MD, Hans-J.ürgen Kaiser, MD, Udalrich Büll, MD and Peter Hanrath, MD, FACC^*

^* Medical Clinic I, University RWTH, Aachen, Germany
Department of Nuclear Medicine, University RWTH, Aachen, Germany
Department of Biomedical Statistics, University Rheinisch Westfälische Technische Hochschule, Aachen, Germany

View larger version (78K): [in a new window]   Figure 1 Strain rate imaging of the septal wall at rest (upper) and during dobutamine stimulation (lower). The color changes from green to yellow for the mid-anterior segment, indicating an increase of contractility. This segment has been shown to be viable by 18F-fluorodeoxyglucose positron emission tomography.

View larger version (20K): [in a new window]   Figure 2 Strain rate tracings at rest (solid line) and during dobutamine stimulation (dotted line) for one cardiac cycle of a hypokinetic segment at rest, shown to be viable by 18FDG PET. There is an increase in the peak systolic strain rate from 1.1 1/s at rest to 2.0 l/s during dobutamine stimulation.

View larger version (29K): [in a new window]   Figure 3 Plot of increase in strain rate during dobutamine stimulation determined by strain rate imaging and increase in tissue velocities during dobutamine stimulation determined by tissue Doppler imaging for myocardial segments defined as normal or viable and for those defined as nonviable by 18F-fluorodeoxyglucose positron emission tomography.