This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Barnes, E. Articles by Camici, P. G. Search for Related Content PubMed PubMed Citation Articles by Barnes, E. Articles by Camici, P. G.

Absolute blood flow and oxygenconsumption in stunned myocardiumin patients with coronary artery disease

^* MRC Clinical Sciences Centre and Division of Cardiology, National Heart and Lung Institute, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom

View larger version (14K): [in a new window]   Figure 1 Study protocol demonstrating the relative timings for the positron emission tomography and echocardiographic acquisitions. C15O = 15O-labelled carbon monoxide; H215O = 15O-labelled water; TR = transmission scan; 15O2 = 15O-labelled oxygen.

View larger version (17K): [in a new window]   Figure 2 (A) Ejection fraction (%) versus time after peak dobutamine (mean ± 95% confidence interval [CI]). (B) Shortening fraction of dysfunctional and non-dysfunctional remote regions (mean ± 95% CI). SFdysfunction = post-ischemic dysfunction; SFnorm = remote regions not demonstrating post-ischemic dysfunction. *p < 0.001; p < 0.05.

View larger version (35K): [in a new window]   Figure 3 (A and B) Myocardial blood flow (MBF) to dysfunctional and remote regions at baseline, peak dobutamine and in recovery. Flow is given as raw data (A) and corrected for the rate pressure product (RPP) (MBFcorr = (MBFbaseline/RPP) x 104). (B) All recovery flow = NS compared with baseline except remote uncorrected flow: (*p < 0.001 compared with baseline uncorrected flow). (C) Myocardial oxygen consumption to dysfunctional and remote regions at baseline and in recovery: (*p < 0.001 compared with corresponding baseline value). SFdysfunction = post-ischemic dysfunction; SFnorm = regions not demonstrating post-ischemic dysfunction.

View larger version (22K): [in a new window]   Figure 4 (A) Shortening fraction (SF) as a percentage change from baseline (mean ± 95% confidence interval [CI]). *p < 0.001. (B) Peak myocardial blood flow (MBF) (mean ± 95% CI) versus stenosis severity (% of luminal diameter) in nine patients.