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Percutaneous coronary intervention versus coronary bypass graft surgery for patients with medically refractory myocardial ischemia and risk factors for adverse outcomes with bypass

the VA AWESOME multicenter registry: comparison with the randomized clinical trial

Investigators of the Department of Veterans Affairs Cooperative Study #385 the Angina With Extremely Serious Operative Mortality Evaluation (AWESOME), Douglass A. Morrison, MD, FACC^*,*, Gulshan Sethi, MD, FACC,^*, Jerome Sacks, PhD,, William Henderson, PhD,, Frederick Grover, MD, FACC,, Steven Sedlis, MD, FACC,, Rick Esposito, MD,, Kodagundi B. Ramanathan, MD, FACC,^||, Darryl Weiman, MD,^||, J. David Talley, MD, FACC,^¶, Jorge Saucedo, MD,^¶, Tamim Antakli, MD,^¶, Venki Paramesh, MD,^*, Stuart Pett, MD,^#, Sarah Vernon, MD, FACC,^#, Vladimir Birjiniuk, MD,^**, Frederick Welt, MD,^**, Mitchell Krucoff, MD, FACC,, Walter Wolfe, MD, FACC,, John C. Lucke, MD,, Sundeep Mediratta, MD,, David Booth, MD, FACC,, Charles Barbiere, CCRN, Dan Lewis, MDFACC^||||

^* Tucson VA Medical Center, Tucson, Arizona, USA
CSPCC Hines VA Hospital, Hines, Illinois, USA
Denver VA Medical Center, Denver, Colorado, USA
New York VA Medical Center, New York, New York, USA
^|| Memphis VA Medical Center, Memphis, Tennessee, USA
^¶ Little Rock VA Medical Center, Little Rock, Arkansas, USA
^# Albuquerque VA Medical Center, Albuquerque, New Mexico, USA
^** West Roxbury VA Medical Center, West Roxbury, Massachusetts, USA
Durham VA Medical Center, Durham, North Carolina, USA
Asheville VA Medical Center, Asheville, North Carolina, USA
Lexington VA Medical Center, Lexington, Kentucky, USA
^|||| Kansas City VA Medical Center, Kansis City, Kansas, USA

View larger version (17K): [in a new window]   Figure 1 Kaplan-Meier plots of survival for coronary artery bypass graft surgery (CABG) (circle) versus percutaneous coronary intervention (PCI) (x) in physician-directed registry. Numbers of patients and survival are given at the bottom.

View larger version (17K): [in a new window]   Figure 2 Kaplan-Meier plots of survival for coronary artery bypass graft surgery (CABG) (circle) versus percutaneous coronary intervention (PCI) (x) in patient-choice registry. Numbers of patients and survival are given at the bottom.

View larger version (18K): [in a new window]   Figure 3 Kaplan-Meier plots of survival free of unstable angina for coronary artery bypass graft surgery (CABG) (circle) versus percutaneous coronary intervention (PCI) (x) in physician-directed registry. Numbers of patients and survival are given at the bottom.

View larger version (17K): [in a new window]   Figure 4 Kaplan-Meier plots of survival free of unstable angina for coronary artery bypass graft surgery (CABG) (circle) versus percutaneous coronary intervention (PCI) (x) in patient-choice registry. Numbers of patients and survival are given at the bottom.

View larger version (18K): [in a new window]   Figure 5 Kaplan-Meier plots of survival free of unstable angina and repeat revascularization for coronary artery bypass graft surgery (CABG) (circle) versus percutaneous coronary intervention (PCI) (x) in physician-directed registry. Numbers of patients and survival are given at the bottom.

View larger version (17K): [in a new window]   Figure 6 Kaplan-Meier plots of survival free of unstable angina and repeat revascularization for coronary artery bypass graft surgery (CABG) (circle) versus percutaneous coronary intervention (PCI) (x) in patient-choice registry. Numbers of patients and survival are given at the bottom.