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Contribution of nicotine to acute endothelial dysfunction in long-term smokers

Thomas Neunteufl, MD^*,*, Sandra Heher, MD^*, Karam Kostner, MD^*, Goran Mitulovic, PhD, Stephan Lehr, Gholamali Khoschsorur, PhD, Rainer W. Schmid, PhD, Gerald Maurer, MD, FACC^* and Thomas Stefenelli, MD, FACC^*

^* Department of Cardiology, University of Vienna, Vienna, Austria
Clinical Chemistry, University of Vienna, Vienna, Austria
Institute for Medical Statistics, University of Vienna, Vienna, Austria
Institute of Biochemistry, University of Graz, Graz, Austria

View larger version (17K): [in a new window]   Figure 1 Flow-mediated dilation (FMD) values before and after the administration of nicotine nasal spray (1-mg nicotine) and smoking a cigarette (1-mg nicotine, 12-mg tar), respectively.