Noninvasive assessment of microvascular function in arterial hypertension by transthoracic doppler harmonic echocardiography
Thomas Bartel, MD*,*,
Y. a Yang, MD*,
Silvana Müller, MD ,
René R. Wenzel, MD ,
Dietrich Baumgart, MD*,
Thomas Philipp, MD and
Raimund Erbel, MD, FACC*
* Cardiology Division, Department of Internal Medicine, University of EssenEssen, Germany
Cardiology Division, Department of Internal Medicine, University of Innsbruck, Innsbruck, Austria
Division of Nephrology and Hypertension, Department of Internal Medicine, University of Essen, Essen, Germany
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Figure 1 Echocardiographic readings of coronary flow velocity. bAPV = baseline average peak velocity; hAPV = hyperemic average peak velocity.
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Figure 2 Linear regression analyses including Bland-Altman plots of differences (11) between intracoronary and Doppler echocardiographic measurements. Some symbols represent more than one pair of data. (A) Comparison of intracoronary vs. echocardiographic baseline average peak velocity (bAPV) in group 1 and group 2; (B) comparison of intracoronary vs. echocardiographic hyperemic average peak velocity (hAPV) in both groups; (C) comparison of intracoronary vs. echocardiographic coronary flow velocity reserve (CFVR) in both groups. Open circle = group 1; filled circle = group 2. ICD = intracoronary Doppler; SD = standard deviation; SEE = standard error of estimate; TTDHE = transthoracic Doppler harmonic echocardiography.
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Figure 3 Calculation of the optimal cutoff point between group 1 and group 2 by use of receiver operating characteristic curve with respect to coronary flow velocity reserve. Dotted line shows a random distribution. AUC = area under the receiver operating characteristic curve; SEM = standard error of the mean.
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