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Prognostic significance of left ventricular diastolic dysfunction in essential hypertension

Giuseppe Schillaci, MD^*,*, Leonella Pasqualini, MD^*, Paolo Verdecchia, MD, FACC, Gaetano Vaudo, MD^*, Simona Marchesi, MD^*, Carlo Porcellati, MD, Giovanni de Simone, MD, FACC and Elmo Mannarino, MD^*

^* Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
Department of Cardiology, Perugia General Hospital, Perugia, Italy
Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy

View larger version (33K): [in a new window]   Figure 1 Bivariate relationships of the early/atrial (E/A) mitral velocity ratio with age, heart rate, left ventricular mass index and 24-h systolic blood pressure. All p < 0.001.

View larger version (19K): [in a new window]   Figure 2 Cardiovascular event-free survival in hypertensive patients whose unadjusted (upper panel) or age- and heart rate-adjusted (lower panel) early/atrial (E/A) mitral velocity ratio was below or above the median value.