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Early angioplasty in acute coronary syndromes without persistent st-segment elevation improves outcome but increases the need for six-month repeat revascularization

An analysis of the pursuit trial

Eelko Ronner, MD, PhD^*, Eric Boersma, PhD^*, Gert-Jan Laarman, MD, PhD, G. Aernout Somsen, MD, PhD, Robert A. Harrington, MD, PhD, Jaap W. Deckers, MD, PhD^*, Eric J. Topol, MD, PhD^||, Robert M. Califf, MD, PhD and Maarten L. Simoons, MD, PhD^*,*

^* University Hospital Rotterdam, Rotterdam, The Netherlands
Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
Academic Medical Center, Amsterdam, The Netherlands
Duke Clinical Research Institute, Durham, North Carolina, USA
^|| Cleveland Clinic Foundation, Cleveland, Ohio, USA

View larger version (19K): [in a new window]   Figure 1 Death and myocardial infarction at 30 days, according to the time of percutaneous coronary intervention (PCI).

View larger version (12K): [in a new window]   Figure 2 Occurrence (%) of cardiac complications in patients undergoing percutaneous coronary intervention from day 0 to 30, randomly assigned to glycoprotein IIb/IIIa inhibition (open bars) or placebo (solid bars) for 72 h. MI = myocardial infarction.