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Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure

Tamara B. Horwich, MD^*, Gregg C. Fonarow, MD, FACC^,*, Michele A. Hamilton, MD, FACC, W. Robb MacLellan, MD, FACC and Jeff Borenstein, MD

^* Department of Medicine, University of California, Los Angeles, USA
Ahmanson–University of California Cardiomyopathy Center, Los Angeles, USA
Cedars–Sinai Health System, Los Angeles, California, USA

View larger version (17K): [in a new window]   Figure 1 Kaplan-Meier survival analysis for the entire cohort by quartile of hemoglobin (Hb) level.

View larger version (17K): [in a new window]   Figure 2 Mortality for the entire cohort by decile of hemoglobin level.

View larger version (41K): [in a new window]   Figure 3 Mortality by hemoglobin quartile (Q) for the total cohort compared to subgroups of men (Q1 <12.6; Q2 12.6–13.9; Q3 14.0–15.0; Q4 >15.0 g/dl) and women (Q1 <11.6; Q2 11.6–12.6; Q3 12.7–13.8; Q4 >13.8 g/dl), patients with ischemic and nonischemic cardiomyopathy (CMY), and excluding patients who underwent urgent or elective status transplantation.