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Prognostic significance of elevated troponin i after percutaneous coronary intervention

Warren J. Cantor, MD^*,*, L. Kristin Newby, MD, FACC, Robert H. Christenson, PhD, Robert H. Tuttle, MSPH, Vic Hasselblad, PhD, Paul W. Armstrong, MD, FACC, David J. Moliterno, MD, FACC^||, Robert M. Califf, MD, FACC, Eric J. Topol, MD, FACC^||, E. Magnus Ohman, MD, FACC the SYMPHONY and 2nd SYMPHONY Cardiac Markers Substudy Investigators

^* St. Michael’s Hospital, Division of Cardiology, Toronto, Ontario, Canada
Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
Department of Pathology, University of Maryland Medical System, Baltimore, Maryland, USA
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
^|| Cleveland Clinic Foundation, Cleveland, Ohio, USA

View larger version (14K): [in a new window]   Figure 1 Kaplan-Meier curve for freedom from death or myocardial infarction (MI) after percutaneous coronary intervention, by postprocedural troponin status. cTnI = cardiac troponin I.

View larger version (20K): [in a new window]   Figure 2 Unadjusted hazard ratios and 95% confidence intervals for the risk of events 90 days after percutaneous coronary intervention by postprocedural cardiac troponin I (cTnI) status. Hazard ratios are depicted for the primary analysis population (n = 481) and for patients with negative preprocedural cTnI (n = 151). CK-MB = creatine kinase-MB; MI = myocardial infarction; SRI = severe recurrent ischemia.