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Continued symptomatic improvement three to five years after transmyocardial revascularization with co₂ laser

A late clinical follow-up of the norwegian randomized trial with transmyocardial revascularization

Lars Aaberge, MD^*,*, Kjell Rootwelt, MD, PhD, Svein Blomhoff, MD, PhD, Kjell Saatvedt, MD, PhD, Michel Abdelnoor, MPH, PhD^|| and Kolbjorn Forfang, MD, PhD^*

^* Department of Cardiology, Rikshospitalet University Hospital, Oslo, Norway
Department of Clinical Chemistry/Section of Nuclear Medicine, Rikshospitalet University Hospital, Oslo, Norway
Department of Psychiatry, Rikshospitalet University Hospital, Oslo, Norway
Feiringklinikken, Feiring, Oslo, Norway
^|| Ullevaal University Hospital, Oslo, Norway

View larger version (20K): [in a new window]   Figure 1 Left ventricular ejection fraction (LVEF) after transmyocardial revascularization with CO2 laser compared with medical treatment. Left ventricular ejection fraction in 63 of 75 patients (84%) with complete multiple-gated acquisition investigations during follow-up; LVEF values are given as mean ± SD. No statistically significant difference between the groups during follow-up. Black bar = TMR (n = 33); lined bar = medical treatment (n = 30).

View larger version (19K): [in a new window]   Figure 2 Quality of life (MOS 36 Short-Form Health Survey) during 12 months’ follow-up. Summary physical component scale (PCS) and summary mental component scale (MCS) in the medical treatment (MT) group and transmyocardial revascularization with CO2 laser (TMR) group during 12 months follow-up. Higher values indicate improved quality of life. *Statistical significance between groups, comparing the changes between the groups from baseline to 3, 6 and 12 months, respectively.

View larger version (24K): [in a new window]   Figure 3 Summary physical component scales (PCS) in patients with different angina classifications. Higher values indicate improved quality of life. Values are given as mean ± SD. *Statistical significance between patients classified as New York Heart Association (NYHA) functional class II and class III and between NYHA functional class III and class IV. Lined bar = all; shaded bar = transmyocardial revascularization with CO2 laser; black bar = medical treatment. *p < 0.01.