Echo-Doppler mitral flow monitoring: an operative tool to evaluate day-to-day tolerance to and effectiveness of beta-adrenergic blocking agent therapy in patients with chronic heart failure
Soccorso Capomolla, MD*,a,
GianDomenico Pinna, MSa,
Oreste Febo, MDa,
Angelo Caporotondi, MDa,
Giampaolo Guazzotti, MDa,
Maria Teresa La Rovere, MDa,
Marco Gnemmi, MDa,
Andrea Mortara, MDa,
Roberto Maestri, MSa and
Franco Cobelli, MDa
a Fondazione "Salvatore Maugeri," Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Scientifico di Montescano, Pavia, Italy

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Figure 1 Schematic diagram of the titration profile of the patients enrolled in the study according to baseline mitral flow pattern (MFP) and its acute change after loading manipulations. NTP = nitroprusside infusion; PLL = passive leg lifting.
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Figure 2 Kaplan-Meier survival curves for the combined end point of cardiac mortality or urgent heart transplantation or readmission for congestive heart failure. Patients were stratified according to the chronic change of the mitral flow pattern after six months of beta-adrenergic blocking agent treatment. MFP = mitral flow pattern.
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