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Flow-mediated vasodilation of the femoral and brachial artery induced by exercise in healthy nonsmoking and smoking men

^a Department of Internal Medicine, University of Innsbruck, Innsbruck, Austria

View larger version (34K): [in a new window]   Figure 1 Exercise-induced changes of the femoral (a) and brachial (b) artery diameter in nonsmoking (black circles) and smoking (white circles) subjects. (a) Evaluation of the femoral artery diameter during exercise by repeated measures analysis of variance (ANOVA) showed significant changes in both nonsmoking and smoking subjects (p < 0.001). Comparison of the line plots of both study groups were performed by using linear regression analyses and revealed significantly different slopes of femoral artery diameter increases. (b) Evaluation of brachial artery diameter changes during exercise by repeated measures ANOVA gave p values of 0.03 and 0.09 for nonsmoking and smoking subjects, respectively. Comparison of the line plots of both study groups were performed by linear regression analyses and revealed no significant difference between the slopes of brachial artery diameter increases. *p < 0.05 and p < 0.001 for comparison to baseline.

View larger version (31K): [in a new window]   Figure 2 Exercise-induced changes of the femoral (a) and brachial (b) artery blood flow in nonsmoking (black circles) and smoking (white circles) subjects. Evaluation of femoral and brachial artery blood flow during exercise by repeated measures analysis of variance showed significant changes in both nonsmoking and smoking subjects (p < 0.001). Comparison of the line plots of both study groups were performed by linear regression analyses and revealed no significant difference between the slopes of femoral and brachial artery blood flow increases. *p < 0.05, p < 0.01, and p < 0.001 for comparison to baseline.

View larger version (16K): [in a new window]   Figure 3 Correlation between flow-mediated dilation of the femoral artery (FMD FA) induced by exercise and flow-mediated dilation of the brachial artery (FMD BA) induced by forearm cuff occlusion.