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J Am Coll Cardiol, 2001; 38:1313-1319
© 2001 by the American College of Cardiology Foundation
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Flow-mediated vasodilation of the femoral and brachial artery induced by exercise in healthy nonsmoking and smoking men

Hannes Gaenzer, MD*,a, Guenther Neumayr, MDa, Peter Marschang, MDa, Wolfgang Sturm, MDa, Rudolf Kirchmair, MDa and Josef R. Patsch, MDa

a Department of Internal Medicine, University of Innsbruck, Innsbruck, Austria



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  		Figure 1 Exercise-induced changes of the femoral (a) and brachial (b) artery diameter in nonsmoking (black circles) and smoking (white circles) subjects. (a) Evaluation of the femoral artery diameter during exercise by repeated measures analysis of variance (ANOVA) showed significant changes in both nonsmoking and smoking subjects (p < 0.001). Comparison of the line plots of both study groups were performed by using linear regression analyses and revealed significantly different slopes of femoral artery diameter increases. (b) Evaluation of brachial artery diameter changes during exercise by repeated measures ANOVA gave p values of 0.03 and 0.09 for nonsmoking and smoking subjects, respectively. Comparison of the line plots of both study groups were performed by linear regression analyses and revealed no significant difference between the slopes of brachial artery diameter increases. *p < 0.05 and {ddagger}p < 0.001 for comparison to baseline.

 


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  		Figure 2 Exercise-induced changes of the femoral (a) and brachial (b) artery blood flow in nonsmoking (black circles) and smoking (white circles) subjects. Evaluation of femoral and brachial artery blood flow during exercise by repeated measures analysis of variance showed significant changes in both nonsmoking and smoking subjects (p < 0.001). Comparison of the line plots of both study groups were performed by linear regression analyses and revealed no significant difference between the slopes of femoral and brachial artery blood flow increases. *p < 0.05, {dagger}p < 0.01, and {ddagger}p < 0.001 for comparison to baseline.

 


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  		Figure 3 Correlation between flow-mediated dilation of the femoral artery (FMD FA) induced by exercise and flow-mediated dilation of the brachial artery (FMD BA) induced by forearm cuff occlusion.

 




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