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J Am Coll Cardiol, 2001; 38:1116-1122
© 2001 by the American College of Cardiology Foundation
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Anti-ischemic effects of angiotensin- converting enzyme inhibition in hypertension

Abhiram Prasad, MD, MRCPa, Rita Mincemoyer, RNa and Arshed A. Quyyumi, MD, FRCP, FACCa

a Cardiology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA



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Figure 1 Change in ischemic threshold (rate-pressure product [RPP]) and duration of exercise at the onset of 1-mm ST-depression in hypertensive and normotensive patients before (open bars) and after (solid bars) treatment with enalapril.

 


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Figure 2 Change in duration of exercise, workload and ST depression at peak exercise, before (open bars) and after (solid bars) with enalapril. METS = metabolic equivalents.

 


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Figure 3 Change in forearm blood flow and vascular resistance in response to bradykinin before (open circles) and after (solid circles) enalapril therapy in hypertensive and normotensive patients. The p values compare bradykinin responses by analysis of variance.

 




 
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