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J Am Coll Cardiol, 2001; 38:1007-1011
© 2001 by the American College of Cardiology Foundation
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Diabetes mellitus prevents ischemic preconditioning in patients with a first acute anterior wall myocardial infarction

Masaharu Ishihara, MD, PhDa, Ichiro Inoue, MD, PhDa, Takuji Kawagoe, MD, PhDa, Yuji Shimatani, MDa, Satoshi Kurisu, MDa, Kenji Nishioka, MDa, Yasuyuki Kouno, MDa, Takashi Umemura, MDa, Syuji Nakamura, MDa and Hikaru Sato, MD, PhDa

a Department of Cardiology, Hiroshima City Hospital, Hiroshima, Japan



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Figure 1 Peak creatine kinase value was significantly smaller in non-diabetic patients with prodromal angina (solid bars) than it was in non-diabetic patients without (open bars). It was not significantly different between diabetic patients with prodromal angina and diabetic patients without.

 


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Figure 2 Acute left ventricular ejection fraction (LVEF), predischarge LVEF and the change in LVEF in non-diabetic patients with prodromal angina (solid bars) and non-diabetic patients without (open bars). Acute LVEF was not significantly different, but predischarge LVEF and the change in LVEF were significantly better in non-diabetic patients with prodromal angina than in non-diabetic patients without.

 


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Figure 3 In-hospital mortality was significantly lower in non-diabetic patients with prodromal angina (solid bars) than in non-diabetic patients without (open bars). There was no significant difference in in-hospital mortality between diabetic patients with, and diabetic patients without, prodromal angina.

 


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Figure 4 Acute left ventricular ejection fraction (LVEF), predischarge LVEF and the change in LVEF in diabetic patients with prodromal angina (solid bars) and in diabetic patients without (open bars). Acute LVEF, predischarge LVEF and the change in LVEF were not significantly different between diabetic patients with prodromal angina and diabetic patients without.

 





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