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The relationship between obesity and mortality in patients with heart failure

Tamara B. Horwich, MD^*, Gregg C. Fonarow, MD, FACC, Michele A. Hamilton, MD, FACC, W. Robb MacLellan, MD, FACC, Mary A. Woo, DNSc and Jan H. Tillisch, MD^*

^* Department of Medicine, University of California at Los Angeles Medical Center, Los Angeles, California, USA
Ahmanson-UCLA Cardiomyopathy Center, Division of Cardiology, University of California at Los Angeles Medical Center, Los Angeles, California, USA
School of Nursing, University of California at Los Angeles Medical Center, Los Angeles, California, USA

View larger version (26K): [in a new window]   Figure 1 Actuarial survival curves for the four body mass index (BMI) categories at five years. Survival, free of urgent heart transplantation or death, was not statistically different for any of the four BMI categories (p = 0.9383).

View larger version (25K): [in a new window]   Figure 2 Risk-adjusted survival curves for the four body mass index (BMI) categories at five years. The variables entered into the equation were age, gender, hypertension, diabetes mellitus, left ventricular ejection fraction, hemodynamic variables, peak O2), mitral regurgitation, tricuspid regurgitation, medications and serum sodium, creatinine and lipid levels. Survival was significantly better for the overweight and obese BMI categories.