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Clinical and quantitative coronary angiographic predictors of coronary restenosis

A comparative analysis from the balloon-to-stent era

Nestor Mercado, MD, DSc^*,1, Eric Boersma, PhD^*, William Wijns, MD, PhD, Bernard J. Gersh, MB, DPhil, ChB, FACC, Carlos A. Morillo, MD, Vincent de Valk, PhD^||, Gerrit-Anne van Es, PhD^||, Diederick E. Grobbee, MD, PhD^¶ and Patrick W. Serruys, MD, PhD, FACC^*

^* Thoraxcenter, University Hospital Dijkzigt, Rotterdam, The Netherlands
Cardiovascular Center, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
Department of Cardiology, Fundacion Cardiovascular del Oriente Colombiano, Bucaramanga, Colombia
^¶ Julius Center for Patient Oriented Research, University Medical Center, Utrecht, The Netherlands
^|| Cardialysis, Rotterdam, The Netherlands

View larger version (22K): [in a new window]   Figure 1 Univariate analysis of demographic, clinical and quantitative coronary angiography (QCA) predictors of coronary restenosis. When a common odds ratio (OR) is presented, the interaction term between stent use and each of the variables was not significant (p 0.001), and then this is the OR (and its corresponding 95% confidence interval [CI]) for the percutaneous transluminal coronary angioplasty (PTCA) and stent populations (solid circles). The interaction term between stent use and each of the variables was significant (p < 0.001) if the PTCA (solid triangles) and stent (solid squares) populations each had two ORs (with 95% CIs) presented. AMI = acute myocardial infarction; BMI = body mass index; CABG = coronary artery bypass graft surgery; CSA = chronic stable angina; DM = diabetes mellitus; DS = diameter stenosis; HTA = hypertension; LAD = left anterior descending coronary artery; LCx = left circumflex coronary artery; MI = myocardial infarction; MLD = minimal lumen diameter; MVD = multi-vessel disease; PVD = peripheral vascular disease; RCA = right coronary artery; RD = reference diameter; UA = unstable angina.