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Rapid evaluation of left ventricular volume and mass without breath-holding using real-time interactive cardiac magnetic resonance imaging system

Shuichiro Kaji, MD^*, Philip C. Yang, MD^*, Adam B. Kerr, PhD, W. H. Wilson Tang, MD^*, Craig H. Meyer, PhD, Albert Macovski, PhD, John M. Pauly, PhD, Dwight G. Nishimura, PhD and Bob S. Hu, MD, FACC^*

^* Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, California, USA
Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California, USA

View larger version (115K): [in a new window]   Figure 1 Short-axis magnestic resonance imaging (MRI) of a heart-failure patient obtained with conventional cine MRI (A: end-diastole; B: end-systole) and real-time MRI (C: end-diastole; D: end-systole).

View larger version (34K): [in a new window]   Figure 2 (A,C) Scattergram shows correlation between conventional cine magnetic resonance (MR) imaging measurements and real-time MR imaging measurements of left ventricular (A) end-diastolic and (C) end-systolic volume in heart-failure patients (n = 9). (B,D) Plots of the average mean versus the differences between cine MR imaging and real-time MR imaging. In A and C, the solid line is the regression line; the dashed line is the line of the identity; in B and D, the solid line is the mean difference; the dashed lines are 2 SD of the mean difference.

View larger version (32K): [in a new window]   Figure 3 (A,C) Scattergram shows correlation between conventional cine magnetic resonance (MR) imaging measurements and real-time MR imaging measurements of ejection fraction (A) and left ventricular mass (C) in heart-failure patients (n = 9). (B,D) Plots of the average mean versus the differences between cine MR imaging and real-time MR imaging. Solid and dashed lines as in Figure 2.

View larger version (34K): [in a new window]   Figure 4 (A,C) Scattergram shows correlation between conventional cine magnetic resonance (MR) imaging measurements and real-time MR imaging measurements of left ventricular (A) end-diastolic and (C) end-systolic volume in healthy volunteers (n = 14). (B,D) Plots of the average mean versus the differences between cine MR imaging and real-time MR imaging. Solid and dashed lines as in Figure 2.

View larger version (33K): [in a new window]   Figure 5 (A,C) Scattergram shows correlation between conventional cine magnetic resonance (MR) imaging measurements and real-time MR imaging measurements of ejection fraction (A) and left ventricular mass (C) in healthy volunteers (n = 14). (B,D) Plots of the average mean versus the differences between cine MR imaging and real-time MR imaging. Solid and dashed lines as in Figure 2.