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Prognostic evaluation of neurohumoral plasma levels before and during beta-blocker therapy in advanced left ventricular dysfunction

^a Department of Cardiology, Ludwig Boltzmann Institute of Experimental Endocrinology and Ludwig Boltzmann Institute of Cardiovascular Research, University of Vienna, Vienna, Austria

View larger version (10K): [in a new window]   Figure 1 Kaplan-Meier analysis showing survival in 91 heart failure patients who were stratified into two groups according to 50 fmol/ml (n = 30, dashed line) and <50 fmol/ml (n = 61, solid line) plasma B-type natriuretic peptide (BNP) levels at baseline. Mortality was significantly higher (log rank p < 0.0004) in patients with baseline BNP levels 50 fmol/ml (17 deaths) than in patients with BNP levels below this cut-off point (14 deaths).