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Screening patients with chest pain in the emergency department using electron beam tomography: a follow-up study

Demetrios Georgiou, MD, FACC^a, Matthew J. Budoff, MD, FACC, Eric Kaufer, MD, John M. Kennedy, MD, Bin Lu, MD and Bruce H. Brundage, MD, FACC

^a Department of Medicine, Division of Cardiology, Columbia University, College of Physicians and Surgeons, New York, New York, USA
Department of Medicine, Division of Cardiology, Harbor-UCLA Research and Education Institute, Torrance, California, USA
Bend Memorial Clinic, Bend, Oregon, USA

View larger version (19K): [in a new window]   Figure 1 Annualized rates for future cardiovascular events by Cox proportional-hazards regression. Patients with scores >400 had an event rate of 58% over the entire study, with an annualized event rate of 13.9%. This was significantly greater than the 0.6% annual event rate of those with scores of zero (p < 0.001).

View larger version (14K): [in a new window]   Figure 2 Relative risks for total cardiovascular events, using age- and gender-adjusted quartiles by multivariate logistic regression. The relative risk of those patients with high age- and gender-adjusted scores (>75th percentile) was 12-fold higher than those with no or little coronary calcium (0 to 25th percentile). Confidence intervals (95%) are displayed for each quartile.