This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Tsutamoto, T. Articles by Kinoshita, M. Search for Related Content PubMed PubMed Citation Articles by Tsutamoto, T. Articles by Kinoshita, M.

Relationship between tumor necrosis factor-alpha production and oxidative stress in the failing hearts of patients with dilated cardiomyopathy

^a First Department of Internal Medicine, Shiga University of Medical Science, Tsukinowa, Seta, Otsu, Japan

View larger version (17K): [in a new window]   Figure 1 Plasma oxidized low density lipoprotein (oxLDL) concentrations in the aortic root (AO), coronary sinus (CS) and femoral vein (FV) in 8 control subjects and in 22 patients with dilated cardiomyopathy. Open columns represent control subjects; closed columns represent patients with dilated cardiomyopathy. *p < 0.05; **p < 0.01 between the value of normal subjects and patients with dilated cardiomyopathy; #p < 0.01 vs. the value of AO by analysis of variance with the Scheffé F test.

View larger version (21K): [in a new window]   Figure 2 Correlation between the transcardiac gradient of plasma oxidized low density lipoprotein (oxLDL) and left ventricular ejection fraction (LVEF). AO = aortic root; CS = coronary sinus; open triangles represent control subjects; open circles represent patients with dilated cardiomyopathy.

View larger version (22K): [in a new window]   Figure 3 Correlation between the transcardiac gradient of plasma oxidized low density lipoprotein (oxLDL) and left ventricular end-diastolic volume index (LVEDVI). AO = aortic root; CS = coronary sinus; open triangles represent control subjects; open circles represent patients with dilated cardiomyopathy.

View larger version (18K): [in a new window]   Figure 4 Comparison of the transcardiac gradient of oxidized low density lipoprotein (oxLDL) between 6 patients who received carvedilol and 16 patients who did not receive carvedilol. AO = aortic root; CS = coronary sinus. *p < 0.05 vs. carvedilol (–).

View larger version (22K): [in a new window]   Figure 5 Correlation between the transcardiac gradient of plasma tumor necrosis factor-alpha (TNF-alpha) and the transcardiac gradient of plasma oxidized low density lipoprotein (oxLDL) in patients with dilated cardiomyopathy. AO = aortic root; CS = coronary sinus.