This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by von Birgelen, C. Articles by Erbel, R. Search for Related Content PubMed PubMed Citation Articles by von Birgelen, C. Articles by Erbel, R.

Plaque distribution and vascular remodeling of ruptured and nonruptured coronary plaques in the same vessel: an intravascular ultrasound study in vivo

Clemens von Birgelen, MD, PhD^*, Wolfgang Klinkhart, MD^*, Gary S. Mintz, MD, FACC, Alexandra Papatheodorou, MD^*, J.örg Herrmann, MD^*, Dietrich Baumgart, MD^*, Michael Haude, MD^*, Heinrich Wieneke, MD^*, Junbo Ge, MD^* and Raimund Erbel, MD, FACC^*

^* Department of Cardiology, University Essen, Essen, Germany
Washington Hospital Center, Washington, D.C., USA

View larger version (102K): [in a new window]   Figure 1 Example of ruptured and nonruptured plaques in right coronary artery. Intravascular ultrasound (IVUS) images of proximal reference, target site and distal reference of ruptured plaque (A–C) and nonruptured plaque (D–E) are shown on side panels. Sites of IVUS image acquisition are indicated on angiogram (center). Schemes next to IVUS images indicate boundaries of lumen, external elastic membrane and cavity inside ruptured plaque (*). Note eccentric plaque distribution and lumen position at site of plaque rupture (B).

View larger version (30K): [in a new window]   Figure 2 Vascular remodeling data. Compensatory enlargement was predominant remodeling type in ruptured and nonruptured plaques (66% and 48%), whereas shrinkage was most frequently observed in control plaques (48%). Data are absolute frequencies (n = 29 for each group). The remodeling pattern differed significantly among the three groups (p = 0.0002, Fisher exact test); pairwise comparison revealed significant differences between ruptured and nonruptured plaques vs. control plaques (p = 0.0001 and 0.003, respectively). Striped bars: compensatory, Black bars: no remodeling, White bars: shrinkage.