Electrophysiologic characteristics in initiation of paroxysmal atrial fibrillation from a focal area
Tse-Min Lu, MD ,
Ching-Tai Tai, MD* ,
Ming-Hsiung Hsieh, MD*,
Chin-Feng Tsai, MD*,
Yung-Kuo Lin, MD ,
Wen-Chung Yu, MD* ,
Hsuan-Ming Tsao, MD ,
Shih-Huang Lee, MD*,
Yu-An Ding, MD* ,
Mau-Song Chang, MD* and
Shih-Ann Chen, MD*
* Division of Cardiology, Department of Medicine, National Yang-Ming University, School of Medicine, Taipei, Taiwan, People's Republic of China
Division of Cardiology, Veterans General Hospital, Taipei, Taiwan, People's Republic of China

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Figure 1 Comparisons of electrophysiologic characteristics of AF episodes originating from proximal and distal portions of PVs (PV-P, PV-D; [A]), RSPV and LSPV (B), superior and inferior PVs (C) and PVs and SVC (D). AF = atrial fibrillation; AF1 = first cycle length of AF episodes; CI = coupling interval of the first ectopic beat just before the onset of AF; CL = cycle length; LSPV = left superior pulmonary vein; Mean CL = mean cycle length of 15 beats before onset of AF; PI = prematurity index; PV = pulmonary vein; PV-D = pulmonary vein-distal; PV-P = pulmonary vein-proximal; RSPV = right superior pulmonary vein; SVC = superior vena cava.
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Figure 2 Two examples of initiation patterns of AF originating from PVs. (A) The onset of AF episode was preceded by cycle length oscillation, namely long-short cycle sequence due to ectopic beats with post-extrabeat pauses. The arrow points to the earliest activity at LSPV-2. The ectopic beats before the onset of AF originated from the same AF-initiating focus. (B) The onset of AF was not preceded by cycle length oscillation. This AF episode originated from the proximal RSPV (arrow). AF = atrial fibrillation; CS = coronary sinus; HRA = high right atrium; LSPV-O, 2, 3 = ostium, second and third pair of electrodes inside the left superior pulmonary vein, respectively; RSPV-O, D = from the ostium to the distal part of right superior pulmonary vein.
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