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Consequences of overutilization and underutilization of thrombolytic therapy in clinical practice

Michael Mundt Ottesen, MD^*, Lars Køber, MD, DMSc^*, Stig Jørgensen, MD, Christian Torp-Pedersen, MD, DMSc, FACC^* on behalf of the TRACE Study Group

^* Department of Cardiology, Gentofte University Hospital of Copenhagen, Copenhagen, Denmark
Department of Internal Medicine, Amager Hospital of Copenhagen, Copenhagen, Denmark, on behalf of the TRACE Study Group

View larger version (17K): [in a new window]   Figure 1 Flowchart of 6,676 consecutive patients with acute myocardial infarction screened for the TRAndolapril Cardiac Evaluation (TRACE) study. The chart is divided according to indications, contraindications and use of thrombolytic therapy.

View larger version (17K): [in a new window]   Figure 2 Mortality with 95% confidence limits according to whether (hatched) or not (solid) the patients received thrombolytic therapy.