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Detection of subclinical coronary atherosclerosis using two-dimensional, high-resolution transthoracic echocardiography

^a Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, Indiana, USA

View larger version (78K): [in a new window]   Figure 1 Quad screen presenting the LAD segment from a normal volunteer (A) and patient with CAD (B). Arrows point to LAD. Markers on the side of the frames represent scale in centimeters. CAD = coronary artery disease; LAD = left anterior descending coronary artery; LV = left ventricle; RVOT = right ventricular outflow tract.

View larger version (38K): [in a new window]   Figure 2 Bar graph illustrating mean measurements of the LAD wall thickness, luminal diameter and external diameter in the groups of normal volunteers and patients with CAD (A) and LAD wall thickness, luminal diameter and external diameter in the groups of patients with subclinical and significant (obstructive) LAD disease (B). Error bars represent standard deviation. CAD = coronary artery disease; LAD = left anterior descending coronary artery.

View larger version (21K): [in a new window]   Figure 3 Scatter plot showing the correlation between the two readers as well as relation of wall thickness (A) luminal diameter (B) and external diameter (C) between the groups of normal volunteers and patients with CAD. CAD = coronary artery disease.

View larger version (20K): [in a new window]   Figure 4 Scatter plot showing the correlation between the left anterior descending coronary artery wall thickness and external diameter in groups of normal volunteers and patients with CAD. CAD = coronary artery disease.

View larger version (22K): [in a new window]   Figure 5 Wall thickness (A) and external diameter (B) of the left anterior descending coronary artery (LAD) are plotted against age for both normal volunteers and patients with CAD. The effect of age on wall thickness and external diameter of the LAD is very small, as shown by the shallow slopes of the regression lines. CAD = coronary artery disease.