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Fractional flow reserve, absolute and relative coronary blood flow velocity reserve in relation to the results of technetium-99m sestambi single-photon emission computed tomography in patients with two-vessel coronary artery disease

Steven A. J. Chamuleau, MD^*, Martijn Meuwissen, MD^*, Berthe L. F. van Eck-Smit, MD, Karel T. Koch, MD^*, Angelina de Jong, MSc^*, Robbert J. de Winter, MD^*, Carl E. Schotborgh, MD^*, Matthijs Bax, MD^*, Hein J. Verberne, MD, Jan G. P. Tijssen, PhD^* and Jan J. Piek, MD^*,1

^* Department of Cardiology, Academic Medical Center of Amsterdam, Amsterdam, The Netherlands
Department of Nuclear Medicine, Academic Medical Center of Amsterdam, Amsterdam, The Netherlands

View larger version (20K): [in a new window]   Figure 1 Plots for the sensitivity and specificity of CFVR (A), relative CFVR (B) and FFR (C), as calculated with receiver operating characteristics analysis on a per-patient basis (n = 127). The best cut-off value (BCV), defined as the highest sum of sensitivity and specificity, is indicated. CFVR = coronary flow velocity reserve; FFR = fractional flow reserve.