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Postinfarctional remodeling: increased dye intensity in the myocardial risk area after angioplasty of infarct-related coronary artery is associated with reduction of ventricular volumes

Gianni Destro, MD^*, Paolo Marino, MD, Enrico Barbieri, MD, FACC^*, Andrea Zorzi, MD^*, Giovanna Brighetti, MD^*, Massimiliano Maines, MD^*, Monica Carletti, MD^* and Piero Zardini, MD^*

^* Division of Cardiology, University of Verona, Verona, Italy
Cardiology Service, University of Verona, Verona, Italy

View larger version (17K): [in a new window]   Figure 1 Individual changes in muscle videointensity (y-axis) versus changes in minimal descending coronary cross-sectional area (x-axis) before and immediately after percutaneous transluminal coronary angioplasty (PTCA). The 95% confidence intervals (dashed lines) of the densitometric and quantitative angiographic reproducibility are also shown. Twenty-nine patients showed increased muscle videointensity (open circles) after PTCA (group A), while 24 did not (group B, unchanged videointensity, black circles), although the coronary cross-sectional areas of the two groups overlapped.

View larger version (24K): [in a new window]   Figure 2 Increased videointensity and left ventricular (LV) volumes (mean value ± SEM) in the "primary/rescue" percutaneous transluminal coronary angioplasty (PTCA) group (left graph) and in the "late" PTCA group (right graph). A trend for a beneficial effect from increased videointensity was evident in all subgroups, but it reached statistical significance only for the diastolic volume in the "primary/rescue" PTCA group. Ventricular volumes were, on the average, larger in the "late" PTCA group.