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Quantification of renal blood flow with contrast-enhanced ultrasound

Kevin Wei, MD, FACC^* , Elizabeth Le, MD^* , Jian-Ping Bin, MD^*, Matthew Coggins, BA^*, Jerrel Thorpe, RDCS^* and Sanjiv Kaul, MD, FACC^*

^* Cardiac Imaging Center, Charlottesville, Virginia, USA
Cardiovascular Division, University of Virginia School of Medicine, Charlottesville, Virginia, USA

View larger version (72K): [in a new window]   Figure 1 Gray-scale image of the kidney from an animal showing distinct differences in echogenicity between the cortex and medulla (A). (B) The location of regions-of-interest drawn over the cortex (blue) and medulla (green) to derive regional video intensity measurements. See text for details.

View larger version (53K): [in a new window]   Figure 2 Background-subtracted color-coded images obtained from an animal at progressively longer pulsing intervals (A to C), both at baseline and during infusion of dopamine. The corresponding pulsing interval versus video intensity curves from the cortex at both stages are shown in D. See text for details.

View larger version (41K): [in a new window]   Figure 3 Background-subtracted color-coded images obtained from an animal at progressively longer pulsing intervals (A to C), at baseline and in the presence of a flow-limiting renal artery stenosis. The pulsing interval versus video intensity curves obtained from the cortex during both stages are shown in D. See text for details.