Predictors of diffuse and aggressive intra-stent restenosis
Steven L. Goldberg, MD, FACC*,
Arthur Loussararian, MD, FACC*,
Joseph De Gregorio, MD, FACC ,
Carlo Di Mario, MD,
Remo Albiero, MD and
Antonio Colombo, MD, FACC
* Harbor-UCLA Medical Center, Torrance, California, USA
Centro Cuore Columbus, Milan, Italy
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Figure 1 Relationship of type of restenosis with time to follow-up, presented as mean ± standard error of the mean. The more aggressive the restenotic process, the earlier the patient presented with restenosis. When both components of aggressive restenosis were present, the follow-up was earlier than when only one component was present. *p < 0.05 compared with the nonaggressive group.
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Figure 2 Relationship between the type of restenosis and the development of a myocardial infarction within six months. The incidence of myocardial infarction increases as the degree of severity of the restenosis increases. p < 0.05 comparing the nonaggressive group with each of the others.
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Figure 3 Relationship of the severity of the restenosis, defined either as focal versus diffuse or the level of aggressiveness, and the final intra-stent cross-sectional area evaluated by intravascular ultrasound (mean ± SEM). The severity of the restenosis worsens as the final cross-sectional area decreases, using either assessment of the severity of the restenosis process.
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