This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Okamura, A. Articles by Ogihara, T. Search for Related Content PubMed PubMed Citation Articles by Okamura, A. Articles by Ogihara, T.

Additive effects of nicorandil on coronary blood flow during continuous administration of nitroglycerin

Atsunori Okamura, MD^*, Hiromi Rakugi, MD^*, Mitsuru Ohishi, MD^*, Yoshihiro Yanagitani, MD^*, Masumi Shimizu, MD^*, Tadahiko Nishii, MD, Yoshiaki Taniyama, MD^*, Takashi Asai, MD^*, Shin Takiuchi, MD^*, Koichi Moriguchi, MD^*, Masashi Ohkuro, MD^*, Norio Komai, MD^*, Kazuo Yamada, MD, Nozomu Inamoto, MD^*, Atsuhiro Otsuka, MD, Jitsuo Higaki, MD^* and Toshio Ogihara, MD^*

^* Department of Geriatric Medicine, Osaka University Medical School, Suita, Osaka, Japan
Division of Cardiology, Ibaraki Iseikai Hospital, Ibaraki, Osaka, Japan

View larger version (26K): [in a new window]   Figure 1 Protocol design. i.v. = intravenous; NTG = nitroglycerin.

View larger version (22K): [in a new window]   Figure 2 Effects of nitroglycerin (NTG) (solid circles, n = 6) and nicorandil (open circles, n=6) on heart rate (HR), mean arterial pressure (MAP), averaged peak (blood) velocity (APV) and coronary blood flow (CBF) in the group with normal coronary arteries. *p < 0.01 vs. NTG.

View larger version (25K): [in a new window]   Figure 3 Effects of nitroglycerin (NTG) (solid circles, n = 6) and nicorandil (open circles, n = 6) on heart rate (HR), mean arterial pressure (MAP), pulmonary capillary wedge pressure (PCWP), averaged peak (blood) velocity (APV) and coronary blood flow (CBF) in the group with stenotic coronary arteries. *p < 0.01 vs. NTG.