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Lack of efficacy of atenolol for the prevention of neurally mediated syncope in a highly symptomatic population: a prospective, double-blind, randomized and placebo-controlled study

^a Arrhythmia Unit, Cardiology Department, Ramón y Cajal Hospital, Alcalá University, Department of Medicine, Madrid, Spain

View larger version (22K): [in a new window]   Figure 1 Primary hypothesis of the study. Kaplan-Meier estimates of the probability of remaining free of syncopal recurrence (time to first syncopal recurrence) in the patients treated with atenolol or the placebo. Dotted line = atenolol; solid line = placebo.

View larger version (15K): [in a new window]   Figure 2 Analyses of the data stratified by the outcome of tilt-table testing. Kaplan-Meier curves for the patients with tilt positive and tilt negative results, time to first syncopal recurrence in the patients treated with atenolol or the placebo. Dotted line = atenolol; solid line = placebo.