Reduction of exercise-induced myocardial ischemia during add-on treatment with the angiotensin-converting enzyme inhibitor enalapril in patients with normal left ventricular function and optimal beta blockade
Ad F. M. van den Heuvel, MDa,
Peter H. J. M. Dunselman, MD, PhDb,
Tsjerk Kingma, MSca,
Patrick Verhorst, MD, PhDc,
Frans Boomsma, PhDd,
Wiek H. van Gilst, PhDa and
Dirk J. van Veldhuisen, MD, PhD, FACCa
a Department of Cardiology/Thoraxcenter, University Hospital Groningen, Netherlands
b Ignatius Hospital, Breda, Netherlands
c Medisch Spectrum Twente, Enschede, Netherlands
d Department of Internal Medicine I/COEUR, University Hospital Dijkzigt, Rotterdam, Netherlands

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Figure 1 Time to 0.1 mV ST-segment depression at baseline after three and 12 weeks treatment with study medication. Dotted line is placebo group. After 12 weeks the difference between groups is significant (p = 0.036).
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