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Endothelial dysfunction in patients with chronic heart failure: systemic effects of lower-limb exercise training

^a University of Leipzig, Heart Center, Division of Cardiology, Leipzig, Germany

View larger version (15K): [in a new window]   Figure 1 Individual changes of the endothelium-dependent, vasodilative response to ACh at a dose of 30 µg/min at the beginning of the study and after four weeks of ET (left panel) and in control subjects (right panel). The percent changes in ID, as compared with baseline diameter (5% glucose infusion), are provided. *p < 0.001 vs. beginning of study. ##p < 0.001 vs. control group.

View larger version (14K): [in a new window]   Figure 2 Correlation between change (four weeks vs. beginning of study) in peak oxygen consumption (VO2max) and change in endothelium-dependent, vasodilative response (ID at four weeks – ID at beginning of study) to ACh (30 µg/min) in the ET group.