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Impact of right ventricular involvement on mortality and morbidity in patients with inferior myocardial infarction¹

Shamir R. Mehta, MD, FACC^* , John W. Eikelboom, MBBS, FRACP, Madhu K. Natarajan, MD, FACC^* , Rafael Diaz, MD, FACC, Cheelong Yi, MSc, PhD, Raymond J. Gibbons, MD, FACC and Salim Yusuf, DPhil, FACC^*

^* Division of Cardiology, Hamilton Health Sciences Corporation, McMaster University, Hamilton, Canada
Population Health Institute, McMaster University, Hamilton, Canada
Estudios Cardiologicos Latinoamerica, Rosario, Argentina
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

View larger version (30K): [in a new window]   Figure 1 A, Left ventricular infarct size as measured by 99mTc-sestamibi SPECT perfusion imaging. B, Left ventricular ejection fraction (LVEF) as measured by RNA. C, Left ventricular end-systolic volume (LVESV) as measured by RNA. D, Peak CK. RVMI+ and RVMI– refer to patients with inferior MI with and without right ventricular myocardial involvement, respectively.

View larger version (36K): [in a new window]   Figure 2 Meta-analysis of studies of right ventricular (RV) myocardial involvement/infarction. A, Mortality. B, Cardiogenic shock. C, Sustained VT or VF. D, Advanced atrioventricular block. The horizontal axis represents log odds ratio with 95% confidence interval (CI). RVMI+ and RVMI– refer to patients with inferior MI with and without right ventricular myocardial involvement, respectively. RVMI = right ventricular myocardial infarction.