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Early assessment of regional myocardial blood flow and metabolism in thrombolysis in myocardial infarction flow grade 3 reperfused myocardial infarction using carbon-11–acetate

^a Department of Nuclear Medicine, UZ Gasthuisberg, Leuven, Belgium
^b Department of Cardiology, UZ Gasthuisberg, Leuven, Belgium

View larger version (27K): [in a new window]   Figure 1 Linear regression plots comparing ejection fractions (EF) at five days and three months with the acetate perfusion index, acetate metabolic index, NH3 perfusion index and FDG metabolic index. glob. EF 5d = global ejection fraction at five days (%); glob. EF 3m = global ejection fraction at three months (%); fdg = fluorine-18–fluorodeoxyglucose (FDG); perf. = perfusion; met. = metabolic; nh3 = ammonia (NH3).

View larger version (41K): [in a new window]   Figure 2 Multivariate analysis of variance revealed that oxidative metabolism measured with acetate was the only significant predictor for recovery of LV function at three months (*p < 0.05). 1 = patients with normal LV function at five days or significant improvement of LV function at follow-up; 2 = patients with impaired LV function at five days and without recovery of LV function; ACE-meta. ind. = acetate metabolic index; FDG-meta. ind. = FDG metabolic index; NH3-perf. ind. = ammonia perfusion index.