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G20210A mutation in the prothrombin gene and the risk of recurrent venous thromboembolism

J. Shawn Miles, MD^* , Joseph P. Miletich, MD^||, Samuel Z. Goldhaber, MD, Charles H. Hennekens, MD^¶ and Paul M. Ridker, MD^*

^* Leducq Center for Molecular and Genetic Epidemiology of Cardiovascular Disorders, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Division of Cardiovascular Disease, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Division of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
^|| Division of Laboratory Medicine, Washington University School of Medicine, St. Louis, Missouri, USA
^¶ University of Miami School of Medicine, Miami, Florida, USA

View larger version (13K): [in a new window]   Figure 1 Rates of recurrent venous thromboembolism (VTE) based on the presence or absence of the prothrombin and factor V Leiden mutations.