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Contrasting clinical properties and exercise responses in obese and lean hypertensive patients

Michael A. Weber, MD, FACC ^*, Joel M. Neutel, MD and David H. G. Smith, MD

^* State University of New York Downstate Medical Center, Brooklyn, New York, USA
Veterans Affairs Medical Center, Long Beach, California, USA

View larger version (16K): [in a new window]   Figure 1 Correlation coefficients for the relations between left ventricular mass index (LVMI) and plasma renin activity or plasma concentrations of norepinephrine and epinephrine in obese and lean hypertensive patients. The r values are significant by univariate analysis for each of the variables in the lean patients; however, by multivariate analysis, only the plasma renin activity and norepinephrine relations remain in the model.

View larger version (20K): [in a new window]   Figure 2 Changes in plasma renin activity and in plasma norepinephrine (PNE) concentrations during treadmill testing in obese and lean hypertensive patients and normotensive volunteers. By two-way analysis of variance, the differences between the obese and lean patients were significant, but not the differences between hypertensive patients and normotensive subjects