N-acetylcysteine improves coronary and peripheral vascular function
Neil P. Andrews, BMBS, MRCP*,
Abhiram Prasad, MBBS, MRCP* and
Arshed A. Quyyumi, MD, FRCP, FACC*
* Cardiology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
View larger version (17K):
[in a new window]
|
Figure 1 Change in coronary vascular resistance, coronary blood flow and epicardial diameter in response to acetylcholine before (control) and after N-acetylcysteine (NAC). P values compare control versus NAC.
|
|
View larger version (18K):
[in a new window]
|
Figure 2 Change in coronary vascular resistance, coronary blood flow and epicardial diameter in response to sodium nitroprusside before (control) and after N-acetylcysteine (NAC).
|
|
View larger version (16K):
[in a new window]
|
Figure 3 Change in coronary vascular resistance, coronary blood flow and epicardial diameter in response to nitroglycerin before (control) and after N-acetylcysteine (NAC).
|
|
View larger version (16K):
[in a new window]
|
Figure 4 Change in coronary vascular resistance and coronary blood flow in response to intracoronary adenosine before (control) and after N-acetylcysteine (NAC).
|
|
View larger version (11K):
[in a new window]
|
Figure 5 Change in femoral vascular resistance index (FVRI) with acetylcholine (left panel), sodium nitroprusside (middle panel) and nitroglycerin (right panel) before (control) and after N-acetylcysteine (NAC). P values with and without NAC are compared by analysis of variance.
|
|
|
