Postcardioversion atrial electrophysiologic changes induced by oral verapamil in patients with persistent atrial fibrillation
Claudio Pandozi, MDa,
Leopoldo Bianconi, MDa,
Leonardo Calò, MDa,
Antonio Castro, MDa,
Filippo Lamberti, MDa,
Maria Carmela Scianaro, MDa,
Giuseppe Gentilucci, MDa and
Massimo Santini, MDa
a Department of Cardiac Diseases, San Filippo Neri Hospital, Rome, Italy
View larger version (15K):
[in a new window]
|
Figure 1 Relation between ERPs and pacing cycle in total study group: patients in washout and patients pretreated with verapamil. A linear correlation between refractoriness and pacing cycle, with a clear adaptation of ERPs to rate, is present in both patients in washout and patients pretreated with verapamil.
|
|
View larger version (16K):
[in a new window]
|
Figure 2 Mean ERP after constant pacing (300, 400, 500, 600 and 700 ms) and after long–short (600 to 300 ms) and short–long (300 to 600 ms) sequences in patients in washouts. Mean ERP during the long–short sequence is significantly shorter than ERP at 300 ms. This "overshoot" is not bidirectional, because no difference is present between ERP during the short–long sequence and ERP at 600 ms.
|
|
View larger version (16K):
[in a new window]
|
Figure 3 Mean ERP after constant pacing (300, 400, 500, 600 and 700 ms) and after long–short (600 to 300 ms) and short–long (300 to 600 ms) sequences in patients pretreated with verapamil. Mean ERP during the long–short sequence is significantly shorter than ERP at 300 ms in these patients. However, the degree of this "overshoot" is smaller than that observed in patients in washout. The "overshoot" is not bidirectional, because no difference is present between ERP during the short–long sequence and ERP at 600 ms.
|
|
|
