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Carotid artery vasoreactivity in response to sympathetic stress correlates with coronary disease risk and is independent of wall thickness

^a Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, Michigan, USA

View larger version (119K): [in a new window]   Figure 1 Results in a 49-year-old man with CAD. (A) A 2.0% reduction in cross-sectional diameter of the carotid artery occurs at 90 s of foot submersion in ice slush. (B) A 5.84% increase in carotid diameter is detected at 120 s after 0.4 mg of sublingual nitroglycerin. CAD = coronary artery disease; CPT = cold pressor test; diam = diameter.

View larger version (33K): [in a new window]   Figure 2 Comparison of the change in carotid artery diameter in response to the cold pressor test and nitroglycerin in average-risk subjects , high-risk subjects and subjects with CAD. Box with vertical lines = at 60 s of CPT; box with diagonal lines = 120 s after Ntg. CAD = coronary artery disease; CPT = cold pressor test; Ntg = nitroglycerin.