The insertion/deletion polymorphism of the angiotensin-converting enzyme gene determines coronary vascular tone and nitric oxide activity
Abhiram Prasad, MBBS, MRCPa,
Suresh Narayanan, MDa,
Myron A. Waclawiw, PhDa,
Neal Epstein, MDa and
Arshed A. Quyyumi, MD, FRCP, FACCa
a Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA

View larger version (37K):
[in a new window]
|
Figure 1 Effects of acetylcholine and sodium nitroprusside on coronary vascular resistance, coronary blood flow and epicardial diameter according to angiotensin-converting enzyme genotype.
|
|

View larger version (36K):
[in a new window]
|
Figure 2 Effects of acetylcholine and sodium nitroprusside on coronary vascular resistance, coronary blood flow and epicardial diameter according to angiotensin type I receptor genotype.
|
|

View larger version (14K):
[in a new window]
|
Figure 3 Effects of L-NG monomethyl arginine (L-NMMA) on coronary vascular resistance, coronary blood flow and epicardial diameter according to angiotensin-converting enzyme genotype.
|
|
|