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J Am Coll Cardiol, 2000; 36:1565-1571
© 2000 by the American College of Cardiology Foundation
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Weight cycling and high-density lipoprotein cholesterol in women: evidence of an adverse effect

A report from the NHLBI-sponsored WISE study

Marian B. Olson, MSa, Sheryl F. Kelsey, PhDa, Vera Bittner, MD, FACCb, Steven E. Reis, MD, FACCc, Nathaniel Reichek, MD, FACCd, Eileen M. Handberg, PhDe, C. Noel Bairey Merz, MD, FACCf for the Women’s Ischemia Syndrome Evaluation (WISE) Study Group

a Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
b the Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
c the Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
d the Division of Cardiology, Allegheny General Hospital, MCP-Hahnemann School of Medicine, Pittsburgh, Pennsylvania, USA
e the University of Florida, Division of Cardiovascular Medicine, Gainesville, Florida, USA
f the Division of Cardiology, Department of Medicine, Cedars-Sinai Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA



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Figure 1 Box plots of HDL-C levels (mg/dl) by magnitude of weight cycled at least 3 times. Extreme values are at the ends; quartile values are on the corners of the box. p = 0.0025 (general linear model). HDL-C = high-density lipoprotein cholesterol.

 




 
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