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Weight cycling and high-density lipoprotein cholesterol in women: evidence of an adverse effect

A report from the NHLBI-sponsored WISE study

^a Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
^b the Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
^c the Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
^d the Division of Cardiology, Allegheny General Hospital, MCP-Hahnemann School of Medicine, Pittsburgh, Pennsylvania, USA
^e the University of Florida, Division of Cardiovascular Medicine, Gainesville, Florida, USA
^f the Division of Cardiology, Department of Medicine, Cedars-Sinai Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA

View larger version (12K): [in a new window]   Figure 1 Box plots of HDL-C levels (mg/dl) by magnitude of weight cycled at least 3 times. Extreme values are at the ends; quartile values are on the corners of the box. p = 0.0025 (general linear model). HDL-C = high-density lipoprotein cholesterol.